In situ forming implant systems: Kinetics of implant formation and concomitant burst drug release An in situ forming implant system for the treatment of periodontal disease with chemotherapeutics was first patented by Dunn et al in 1990s1. The system comprised of a water insoluble
DMSO in parenteral formulations: a review of opportunities and challenges Dimethyl sulfoxide (DMSO) possesses unique properties which have led to its adoption as an excipient in pharmaceutical formulations and medical devices. DMSO is now incorporated into a number of regulated products for healthcare and drug
This recent publication highlights the emergence of the ‘DMSO-I2 system’ as a green oxidation method. This new class of chemical reactions is gentle, robust, and ecofriendly relative to the established alternatives. Substituted imidazole and regioselctive sulfenylation reactions are highlighted Click here to access the
Mechanism of Action Overview: DMSO as a Skin Penetration Enhancer The Stratum Corneum (SC) provides a strong barrier to human skin and provides resistance against penetration and permeation of active ingredients and drugs. The “brick and mortar” model of skin dates to 1983. In this
Gaylord Chemical reviews the recent advances in the use of DMSO in light-promoted synthesis in the March 2019 issue of Specialty Chemicals Magazine This review article provides instances wherein DMSO facilitates light-induced reactions to produce compounds of interest to pharmaceutical and agrochemical synthetic
Procipient®(Dimethyl Sulfoxide USP, Ph. Eur.) is the only grade of DMSO suitable for Healthcare and Drug Delivery applications. Gaylord Chemical’s USP grade is the only DMSO that is manufactured under cGMP conditions, in compliance with API guidelines (ICH Q7). Procipient is supported by a Type II
Gaylord Chemical has achieved certification to the new ISO 9001:2015 Quality Management System. ISO 9001 is the most widely used quality management standard. It has recently undergone a periodic update to better reflect modern business challenges. Last modified in 2008, the new 2015 version of
The choice of an appropriate container when packaging pharmaceutical dosage forms is very important. You must first understand which materials are compatible with your application. Glass containers are the most common form of packaging for pharmaceuticals.
Please enjoy this article at ScienceDirect.com by Dr. Artie McKim, Vice-President, Technology at Gaylord Chemical.