L.L.C. (GCC) is the world's
leading provider of Dimethyl
Sulfoxide (DMSO) solutions.
Beginning in the early
1960's ,GCC has been dedicated
to the development of new uses
for DMSO. In order to meet
customer-specific needs, GCC
has pioneered the development
of multiple grades of DMSO,
including DMSO USP.
Gaylord Chemical's solutions-
based approach has contributed
to the development and growth of
industries including
pharmaceuticals, hydrocarbons,
electronics, polymers, coatings,
agricultural chemicals, and
industrial cleaners.
Gaylord Chemical's headquarters
are located in Slidell, Louisiana
with manufacturing, research,
and development facilities in
nearby Bogalusa, Louisiana.
GCC remains the only producer
of DMSO in the Western
Hemisphere.
This bulletin summarizes the available industrial hygiene and toxicological
data for Dimethyl Sulfoxide (DMSO). DMSO is an unusually nontoxic
organic solvent that is finding increased use in pharmaceutical synthesis,
the manufacture of electronics, and drug delivery in the body. Its use is
supported by over 45 years of industrial and academic experience.
Contents:
Overview (pages 3-4)
Physical Properties of DMSO (page 5)
DMSO Solubility (page 5)
DMSO Reactivity (page 5)
Acute Toxicity (page 6)
Subchronic Toxicity (page 7)
Skin Exposure (page 7)
Chronic Toxicity (page 7-8)
Human and Animal metabolism (page 8)
Metabolite Toxicity (page 8)
Inhalation (page 8)
Effects on Other Organisms (page 9)
Genotoxicity (page 9-10)
Reproductive and Developmental Toxicity (page 10)
References