in commercially important reactions. Using established references from the chemi-
cal literature, our scientists test reaction systems to ascertain the yield, selectivity,
and reaction rates of DMSO versus other solvents.
The
This is one of the preferred synthetic routes to produce alkenes. There are two
steps to this reaction. The first typically involves de-protonation of a triphenylphos-
phonium halide, followed by addition of the intermediate ylide to a carbonyl. Elimina-
tion of triphenylphosphine oxide provides the alkene product..
yields obtained using
DMSO for a series of hin-
dered cyclohexanones. At
right is an example where
DMSO use provides the
highest yields:
Y
e
l
d
L.L.C. (GCC) is the world's
leading provider of Dimethyl
Sulfoxide (DMSO) solutions.
Beginning in the early
1960's ,GCC has been dedi-
cated to the development of
new uses for DMSO. In or-
der to meet customer-specific
needs, GCC has pioneered
the development of multiple
grades of DMSO, including
DMSO USP.
Gaylord Chemical's solutions
-based approach has contrib-
uted to the development and
growth of industries including
pharmaceuticals, hydro-
carbons, electronics, poly-
mers, coatings, agricultural
chemicals, and industrial
cleaners.
Gaylord Chemical's head-
quarters are located in Slidell,
Louisiana with manufactur-
ing, research, and develop-
ment facilities in nearby
Bogalusa, Louisiana. GCC
remains the only producer of
DMSO in the Western Hemi-
sphere.
and the Wittig Reaction